Filed in archive Studies by Gloria Gamat on May 15, 2006

Allergens stimulate the release of antibodies that attach themselves to mast cells causing these cells to release histamine, causing allergy symptoms like itching of the nose, skin and eyes, sneezing, and wheezing.

The characteristic "Th2 immune response" observed in allergy sufferers is an acquired immune response whose most prominent feature is high antibody production relative to the amount of cytotoxic T cells. Classical antihistamine drugs bind to but do not activate the histamine 1 receptor (H1R), subsequently blocking the allergic response.

Histamine was found to act as an attractant for T cells and with no H1Rs present for histamine to bind to, the T cells were not recruited to the lung or able to cause the characteristic inflammatory allergic response in these mice.

Such advancements in the understanding of the roles of histamine in allergic disease hold potential to currently available drugs that can suppress if not stop the action of histamine and deliver benefits to allergy patients.

This study is published in full in the June issue of the Journal of Clinical Investigation.

Source: EurekAlert

Related Entries:

FDA approves a new class of sleeping pill - 22 July 2005
Stop Lying in Your Profile! - 18 October 2006
Old Heart Drug Digoxin Has New Safer Way to Dose - 17 December 2006
Stop sweating in private - 27 January 2007
How to Stop Teenage Dating Abuse - 13 February 2007
Jaguar's "Stop Gap" Until 2009 - 07 May 2007

« Scoliosis Sytems™, New Ho... | Main | New Insulin-Production Me... »

Permalink: Stop Histamine Action, Stop Allergy

Tags: histamine stop

Trackback: http://publish.creative-weblogging.com/publish/mt-tb.pl/21833

Addthis

Ask

Blinklist

del.icio.us

Digg

Fark

Facebook

Google

Lycos

Ma.gnolia

Mr Wong

Netscape

Netvousz

Newsvine

StumbleUpon

Slashdot

Tailrank

Technorati

Wink

Yahoo

Vote for Stop Histamine Action, Stop Allergy:

Currently 8.40/10
1
2
3
4
5
6
7
8
9
10

Rating: 8.40 out of 5 vote(s) cast.

Add your response to Stop Histamine Action, Stop Allergy:

Name: *

Email: (will never be shown)*

URL:

(* marked fields are required)

Notify me if more comments appear?

Subscribe to Straightfromthedoc newsletter? (Newsletters are sent out weekly).

Remember me

Security Code: *
(Please help us to sort out spam.)

Please enter your comment here: (Sorry, no HTML is allowed - URLs will be made clickable automatically if you add http:// to your URL.)

We welcome your comments, however all comments are moderated. Offensive or off-topic comments will be deleted and not displayed.

Share It

Use the search to look for other interesting posts

Contributors (Last 90 days)

Creative Weblogging (9)

This site has 1564 entries and is powered by Creative Weblogging since July 2005.

Our Editors recommend

Disclaimer

Some of the contents of this site are protected Creative Weblogging Inc. 2004-2010.

Check out our Sponsored Blogs!

Business Computer Blog (UK)

Testimonials

'Thanks, for a very interesting and informative Blog.'

'Thanks for doing this; it's a terrific site.'

'I don't know...but why I don't find such informative and profitable blogs so often, I suspect blogging world is becoming so small that we can't find such lucrative blogs like this one.'