A study that appears in the July 2006 issue of the Journal of Biological Chemistry is the first to show that restricting caloric intake (specifically carbohydrates) may prevent Alzheimer's Disease (AD) by triggering activity in the brain associated with Longevity.

The study was directed by Mount Sinai School of Medicine.

"Both clinical and epidemiological evidence suggests that modification of lifestyle factors such as nutrition may prove crucial to Alzheimer's Disease management," says Giulio Maria Pasinetti, M.D., Ph.D., Professor of Psychiatry and Neuroscience, Director of the Neuroinflammation Research Center at Mount Sinai School of Medicine and lead author of the study.

"This research, however, is the first to show a connection between nutrition and Alzheimer's Disease neuropathy by defining mechanistic pathways in the brain and scrutinizing biochemical functions. We hope these findings further unlock the mystery of Alzheimer's and bring hope to the millions of Americans suffering from this disease."

Read more at Mount Sinai School of Medicine.