novel children's heart valve developed by UCLA Engineering and Mattel Children's Hospital

Filed in archive News , Studies , Treatment on February 19, 2006

Soon, children with congenital heart defects may have an alternative to invasive open heart surgery that will mean less time in the hospital, a quicker recovery and no need to break open the breastbone because of the new collaboration between researchers at the UCLA Henry Samueli School of Engineering and Applied Science and pediatric cardiologists at Mattel Children's Hospital at UCLA.

Using a super-elastic, shape-memory metal alloy called "thin film nitinol," UCLA engineers are developing a collapsible heart valve for children that can be loaded into a catheter, inserted into a vein in the groin area, guided into place and then deployed in a precise location within the heart. As the valve is released from the catheter, it springs back to its original shape and begins to function.

"The unobtrusive leaflets within the valve mean there is no obstruction to blood flow. This smaller, low-profile design is well suited for children and, over time, will potentially allow children born with heart valve defects to experience less pain and live much fuller lives."

"Using catheters and collapsible valves, heart valves can be replaced without stopping the heart, without cutting the chest open and without long recovery times," Levi said. "This will represent a huge improvement in care for children living with a very difficult condition."

The team is seeking to collaborate with industry in order to bring their new valves and stents for children to the market but they admit that it will still be a number of years before the valves will be commercially available.