Grape-Soy Combo: Enhanced Anti-Obesity Effects

Filed in archive Diet , Functional Foods , Studies , Weight Loss on November 29, 2007

You've probably read so many times that soy is healthy. Soy is healthy. And that grape is healthy. Grape is healthy. At least the compounds found in grapes and soy are the ones healthy.




What if you mix grapes with soy? Then you get a smorgashboard of healthy stuff: anti-obesity effects are enhanced.

Well, according to a new research from the University of Georgia, teaming-up genistein from soy and resveratrol from grapes enhances the anti-obesity effects of the individual compounds.

The study used human 3T3-L1 cells to model the development and biochemistry of fat cells, and found that combining the compounds reduced fat cell numbers by 59 and 70 per cent more than genistein and resveratrol alone, respectively.

In addition to enhanced inhibition of the cells by the combination of genistein and resveratrol, compared to the individual compounds, the teaming up of the compounds induced apoptosis (programmed cell death) of the fat cells by 242 per cent, compared to control. The individual compounds at their highest dose both increased apoptosis by only 46 per cent.

The researchers also report that, at a dose of 25 micromoles per litre, the individual compounds reduced the accumulation of lipids by 30 and 20 per cent, respectively. In combination at the same respective doses, lipid accumulation was decreased by 77.9 per cent, they said.

Hmmm...maybe a new diet will come out of this combo?

Find more details from NutraIngredients.