Bioengineered Non-Pathogenic Gut Bacteria May Regulate Food Tolerance

Filed in archive Cases , Studies , Treatment on March 5, 2007

A strain of of Lactococcus lactis (a non-pathogenic gut bacteria), when bioengineered to produce anti-inflammatory interleukin-10 (IL-10) can be a potential regulator for food tolerance, thereby significantly beating food allergies.

...oral administration of this non-pathogenic strain effectively reduced food-induced anaphylaxis (severe allergic response) in mice and suppressed the production of an antibody capable of initiating the most powerful immune reactions.

...these findings open interesting potential options in human beings for the prevention of allergies elicited through sensitization in the gut.

This study has been done by Christophe Frossard and Philippe Eigenmann from the University Hospital of Geneva in collaboration with Lothar Steidler from University College Cork and results have been reported at the Journal of Allergy and Clinical Immunology.

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